Carlyss is a census-designated place in Calcasieu Parish, Louisiana, United States. The population was 5,101 in 2020. It is part of the Lake Charles metropolitan statistical area. Carlyss is located south of the center of Calcasieu Parish at 30°11′34″N 93°22′27″W / 30.19278°N 93.37417°W. It is bordered to the north by the city of Sulphur. Interstate 10 follows …Carlyss is a census-designated place in Calcasieu Parish, Louisiana, United States. The population was 5,101 in 2020. It is part of the Lake Charles metropolitan statistical area. Carlyss is located south of the center of Calcasieu Parish at 30°11′34″N 93°22′27″W / 30.19278°N 93.37417°W. It is bordered to the north by the city of Sulphur. Interstate 10 follows the northern border, with access from exits 20 and 21. I-10 leads east 10 miles to Lake Charles and west 22 miles to Orange, Texas. Louisiana Highway 27 runs through the center of Carlyss, connecting Sulphur to the north with Holly Beach on the Gulf of Mexico, 32 miles to the south.