Researchers have identified the structure of amyloid beta fibrils linked to a rare inherited form of Alzheimer’s disease ...

Researchers have uncovered how certain genetic mutations lead to unique spherical amyloid plaques in inherited forms of ...

Alector is kicking off a resource realignment effort that will include a workforce reduction of around 17%. The biotech ...

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

Alector’s AbbVie-partnered Alzheimer's disease asset has failed to slow disease progression in a phase 2 study, the latest in ...

Neuroinflammation can be caused by a range of factors, including stress, and can lead to irreversible consequences like ...

Wedbush upgraded Voyager Therapeutics (VYGR) to Outperform from Neutral with a price target of $11, up from $7, after ...

“We, at Alector, recognize the importance of advancing therapeutics to treat Alzheimer’s disease and remain committed in our ... in frontotemporal dementia with a progranulin gene mutation is expected ...

Alector's AL002 fails in Phase 2 Alzheimer's trial, halting extension study; focus shifts to other programs as workforce is ...