Researchers have identified the structure of amyloid beta fibrils linked to a rare inherited form of Alzheimer’s disease ...

Researchers have uncovered how certain genetic mutations lead to unique spherical amyloid plaques in inherited forms of ...

Scientists studied 188 people related to someone with ALS caused by a C9ORF72 mutation to identify markers of disease risk in ...

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).

Alector is kicking off a resource realignment effort that will include a workforce reduction of around 17%. The biotech ...

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

Alector’s AbbVie-partnered Alzheimer's disease asset has failed to slow disease progression in a phase 2 study, the latest in ...

Neuroinflammation can be caused by a range of factors, including stress, and can lead to irreversible consequences like ...

Wedbush upgraded Voyager Therapeutics (VYGR) to Outperform from Neutral with a price target of $11, up from $7, after assuming coverage of the ...

Alector's AL002 fails in Phase 2 Alzheimer's trial, halting extension study; focus shifts to other programs as workforce is ...

“We, at Alector, recognize the importance of advancing therapeutics to treat Alzheimer’s disease and remain committed in our ... in frontotemporal dementia with a progranulin gene mutation is expected ...