Conditional knock-out mice in which Myrf is knocked out in the OL lineage cells completely fail to develop CNS myelin ... the Emery laboratory have independently made the surprising discovery that ...

While at the Institute for Myelin and Glia Exploration, the Feltri laboratory researchers applied their experience on conditional mutagenesis to ask if there is cell autonomy in the pathogenesis of ...

(A) Illustration of myelinated nerve fiber and saltatory conduction of action potential. An example of PNS myelinated nerve fiber is shown. (B) Illustration of transverse section of myelinated ...