After mice were fed a drug that destroys myelin, recovery of oligodendrocytes and myelination were delayed in mice lacking the C1QL1 protein. Causing mice to express more C1QL1, however, led to ...

In future studies, Grutzendler's team hopes to use these protein data to see if they can improve some of the abnormalities they found at the myelin-axon interface.

Other major myelin constituents include myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG).

DNA parasite now plays key role in making critical nerve cell protein An RNA has been adopted to help the production of myelin, a key nerve protein.

We investigated whether the presence of serum antibodies against myelin oligodendrocyte glycoprotein (MOG) and myelin basic protein (MBP) in patients with a clinically isolated syndrome predicts ...

Multiple sclerosis (MS) is a heterogeneous, immune-mediated disorder in which the body attacks its own myelin sheath that protects the nerve fibers of the central nervous system (CNS).

Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.

Zasadzinski, Husted and Israelachvili also discovered that the myelin basic protein acts as a patch to fill in any holes in the myelin bilayers.

Expression of myelin basic protein (MBP)—the building block of myelin sheaths—was also lower in the hippocampi of older mice.

The working group has already identified protein molecules such as Sox10 that regulate the formation and preservation of myelin sheaths.