ESPN has forecasted the game through its matchup predictor, and early indications show that the Tigers could suffer its first loss of the season. Ahead of Wednesday’s game, the host Blue Devils have a 66.5% chance to beat Auburn and earn another win for the ACC in this season’s challenge.

Cooper Flagg and the Duke Blue Devils play the Auburn Tigers this week, here's how to catch the NCAA basketball game on TV and where to stream.

No. 9 Duke will host No. 2 Auburn on Wednesday in the SEC/ACC Challenge. The Blue Devils lead the all-time series against the Tigers 3-0, and this week will mark only the second meeting between the programs since the turn of the century.