Lutris Pharma, a clinical stage biopharmaceutical company focused on improving anti-cancer therapies by reducing cutaneous ...

These results validate the importance of EGFR signaling in radiation response ... whether EGFR inhibitors effectively inhibit the key pathways driving EGFR-mediated radioresistance?

Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...

leading to the stabilization of EGFR levels and activation of downstream signaling pathways, such as the AKT pathway, which is essential for tumor growth and survival[2]. This interaction not only ...

The EGFR signaling pathway is one of the key pathways that regulate growth, survival, proliferation, and differentiation of cells. B-Raf is a protein encoded by the BRAF gene and is a downstream ...