The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are their grades for this performance.

Brock Purdy, who missed last week's loss to the Packers with a shoulder injury, will play tonight against the Buffalo Bills according to ESPN's Adam

It was December football Sunday night in Buffalo. Playing in below-freezing temperatures and in the snow, the Buffalo Bills (10-2) defeated the San Francisco 49ers (5-7), 35-10, at Highmark Stadium. The 49ers took an early 3-0 lead in the first quarter,

Josh Allen grabbed at his left hand and jumped in pain after he took on 49ers linebacker De'Vondre Campbell Sr.

Buffalo Bills star quarterback Josh Allen pulled off another mind-blowing touchdown that had the football world buzzing. During the third quarter of

As the snow continued to fall on Buffalo's Highmark Stadium, quarterback Josh Allen hit wide receiver Amari Cooper in the red zone on a quick slant. After being stifled by several San Francisco 49ers defenders, Cooper decided to give his quarterback a chance to shine, and lateraled it to him.