There is one stock he has never sold since buying in 1991, though: American Express ( AXP -0.20%). Buffett owns over 20% of the credit card issuer and bank, making it the second-largest position in the Berkshire Hathaway portfolio. The position trades at a value of $40 billion as of this writing.

Tomorrow’s decisions are likely to be better made by three live and well-directed brains than by a dead hand,” wrote Buffett, whose lifetime giving of over $60 billion makes him likely the most prolific philanthropist ever.