A mom tested positive for fentanyl the same day her 2-year-old son died of a fentanyl and xylazine overdose, Florida authorities said. Melissa Rae Harper, 43, has now been charged with aggravated manslaughter of a child, the Jacksonville Sheriff’s Office announced Jan. 17.

JSO Sheriff T.K. Waters said search warrants and traffic stops led to extensive seizures of fentanyl, cocaine and MDMA as part of "Operation Jacob's Ladder."

A Florida woman was arrested for the death of her 2-year-old so, according to the Jacksonville Sheriff's Office. The boy died from a combined drug intoxication of fentanyl and xylazine, officials said.

A year-long drug bust operation has come to a successful end after the arrest of multiple drug traffickers with cartel connections.

Four South Floridians receive prison sentences for distributing drugs, including fentanyl, linked to fatal overdoses.

A Cape Coral man whose arrest became a "landmark" case in Southwest Florida involving the deadly distribution of fentanyl will spend life behind bars.

A new state-wide report released by Florida Attorney General Ashley Moody Thursday reveals a promising downward trend in opioid-related deaths.

A JSO counter-narcotics trafficking operation dubbed ‘Jacob’s Ladder’ has exposed the presence of one of the oldest global criminal organizations in the world.

Mostly seen on the East Coast in places like Philadelphia, xylazine was created to be used in veterinary offices as a sedative. The drug can cause hours-long blackouts and necrosis of the skin, which can lead to amputation. And its effects can't be reversed by naloxone, a medicine that rapidly reverses an opioid overdose.

Drug deaths are down in Florida, with opioid-related deaths experiencing the most dramatic drop, according to a new report from the Florida Department of Law Enforcement.

Former Florida attorney general Pam Bondi will be facing confirmation hearings Wednesday for her nomination as Donald Trump's AG.

A Florida man was arrested in Mississippi for drug trafficking, authorities said. According to the Lowndes County Sheriff’s Office, deputies stopped a