Decoding Alzheimer’s: The Arctic Mutation’s Role in Unusual Brain Structures
Researchers have uncovered how certain genetic mutations lead to unique spherical amyloid plaques in inherited forms of ...
Neuroscience News12d
Unique Brain Plaques Linked to Alzheimer’s Mutation Decoded
Researchers have identified the structure of amyloid beta fibrils linked to a rare inherited form of Alzheimer’s disease ...
Alector Announces Results from AL002 INVOKE-2 Phase 2 Trial in Individuals with Early Alzheimer’s Disease and Provides Business Update
Alector, Inc. (Nasdaq: ALEC), a clinical-stage biotechnology company pioneering novel, genetically validated therapies for ...
eLife4d
Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production
This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).
FierceBiotech4d
UPDATED: Alector lays off 17% of staff after AbbVie-partnered Alzheimer's asset fails phase 2
Alector’s AbbVie-partnered Alzheimer's disease asset has failed to slow disease progression in a phase 2 study, the latest in ...
Armed robbery in Revesby17d
Alzheimer's Mutation Forms Cottonwool Brain Structures
Why Alzheimer's disease strikes some people but not others is still largely mysterious. But in about one percent of cases ...
Structural analysis shows Alzheimer's disease mutation produces 'cottonwool' structures in the brain
An international collaboration led by RIKEN researchers has discovered how unusual spherical structures form in the brains of ...
The Auburn Plainsman15d
Auburn University researchers test novel Alzheimer’s preventive
New research from Auburn University shows a new drug might be a preventive for Alzheimer’s Disease. The study’s main ...
Chronic stress and joint pain could lead to Alzheimer’s by ‘inflaming your brain’
Neuroinflammation can be caused by a range of factors, including stress, and can lead to irreversible consequences like ...
Stress could be ‘inflaming your brain’ with risk of Alzheimer’s Disease experts warn
Neuroinflammation can cause a range of health issues, many of which may be irreversible if left untreated for too long ...
GlobalData on MSN4d
Alector stock drops after Alzheimer’s drug fails in Phase II trial
"Alector stock drops after Alzheimer’s drug fails in Phase II trial" was originally created and published by Clinical Trials ...
ALS News Today1d
Brain scans may predict ALS risk in C9ORF72 mutation carriers
Scientists studied 188 people related to someone with ALS caused by a C9ORF72 mutation to identify markers of disease risk in ...