The San Francisco 49ers have placed All-Pro running back Christian McCaffrey on injured reserve because of his lingering calf ...

ESPN sources: 49ers officially are placing All-Pro RB Christian McCaffrey on injured reserve due to his calf tightness and ...

The 49ers will indeed be without Christian McCaffrey for the near future. They placed the superstar running back on injured reserve with calf tightness and Achilles tendinitis, according to ESPN.

San Francisco 49ers running back Christian McCaffrey (23 ... strong replacement for McCaffrey. (Photo by Stephen Maturen/Getty Images) McCaffrey’s replacement at running back has been Georgia ...

MINNEAPOLIS -- Whether it's by watching game tape or combing through statistics, Christian McCaffrey's value to ... against the Vikings on Sunday. AP Photo/Abbie Parr It's a small sample but ...

MINNEAPOLIS -- The San Francisco 49ers are certain that they'll be without running back Christian McCaffrey for at least the next three games. And while it could be longer than that before ...

Now, NFL Network insider Ian Rapoport has unveiled a likely worst-case timeline for McCaffrey to return to game action.

They have placed starting running back Christian McCaffrey on ... The Chiefs defeated the 49ers 25-22. McCaffrey is now being placed on IR. More Photo by Michael Zagaris/San Francisco 49ers ...

A week ago, just about everyone assumed San Francisco 49ers star Christian McCaffrey would play in the team’s season opener. Now, he may not play for the first time until after the Super Bowl ...

On Friday, the San Francisco 49ers shared the news that tight end George Kittle may not play on Sunday against the Los ...