The Bills beat the Patriots 24-21 thanks to the performance from starting running back James Cook along with timely plays made by the defense. Cook ran the ball 11 times for 100 yards and one touchdown while also catching three passes for 26 yards and another touchdown, showing his ability to affect the game on the ground and through the air.

The Buffalo Bills defeated the New England Patriots in their first matchup against each other this season. Although the final score was 24-21 with Buffalo on top to finish, the Bills didn’t get their feet under themselves right away.

The Buffalo Bills must keep their foot on the gas. Despite being a long shot to supplant the Kansas City Chiefs for the No. 1 seed in the AFC, there's more at stake.

The Kansas City Chiefs finished the regular season undefeated at home, holding off the AFC South champion Houston Texans 27-19. Depending on the Buffalo Bills' results

The Chiefs hosted the Texans in Week 16, and there was plenty to take away from the Saturday afternoon contest.

The Bills (12-3) can catch the Kansas City Chiefs (14-1) for the top seed if Buffalo wins its final two games and Kansas City loses its last two games. Buffalo could wind up the No. 1, No. 2 or No. 3 seed.

Buffalo will need help to capture the No. 1 overall seed, but it is possible. The Bills hold the head-to-head tiebreaker over the Chiefs, so if Buffalo wins out and the Chiefs drop their last two games, the Bills would top the AFC.

The New England Patriots (3-11) and the Buffalo Bills (11-3) meet Sunday in a Week 16 game at Highmark Stadium. Kickoff is scheduled for 4:25 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's