The myelin basic protein (MBP) peptide of amino acids 83–99 (called MBP (83–99) here) is the best examined and is considered one candidate antigen in MS (refs. 1, 18).

Confocal microscopy confirmed that purified Eos expressing major basic protein (MBP) also stained positive for CLC-P/Gal10 (Fig. 4 b and c). Fig. 4 CLC-P/Gal10 expressed by primary eosinophils impairs ...

In this image, an axon appears in green, while abnormal protein clumps (amyloid, red) lodge in tiny channels within the myelin sheath. Amyloid aggregates form filament-like strands across the ...

These problems—less energy, loss of myelin, and damaged neurons—start early, but the actual death of the brain cells tends to happen later, as the disease becomes more severe.