Lutris Pharma Secures $30 Million Financing to Advance the Development of Biopharmaceutical to Improve Anti-Cancer Drug Effectiveness
Lutris Pharma, a clinical stage biopharmaceutical company focused on improving anti-cancer therapies by reducing cutaneous ...
The EMBO Journal10d
Ephrin A1 functions as a ligand of EGFR to promote EMT and metastasis in gastric cancer
Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...
Health Affairs15d
Quality Pathway Implementation At The CMS Innovation Center
Last year, the CMS Innovation Center launched the Quality Pathway strategic initiative to strengthen the focus on quality in alternative payment models. Since it was created, the CMS Innovation ...
Frontiers23d
DET induces apoptosis and suppresses tumor invasion in glioma cells via PI3K/AKT pathway
Enrichment analysis demonstrated that DET influenced the MAPK and PI3K/AKT signaling pathways. In Transwell assays, DET significantly inhibited the invasive behavior of glioma cells. Western blot ...
Frontiers26d
Hyodeoxycholic acid inhibits colorectal cancer proliferation through the FXR/EREG/EGFR axis
And the relationship of HDCA mediating the Epiregulin (EREG)/Epidermal Growth Factor Receptor (EGFR) signaling pathway through FXR was explored. Eight pairs of primary CRC and paracancerous tissue ...
Cancer Research28d
TEAD-Independent Cell Growth of Hippo-Inactive Mesothelioma Cells: Unveiling Resistance to TEAD Inhibitor K-975 through MYC Signaling Activation
1Division of Cancer Biology, Aichi Cancer Center Research Institute, Nagoya, Japan. 2Department of Respiratory Medicine, Fujita Health University School of Medicine, Toyoake, Japan.
C&EN29d
Image-Based Phenotypic Profiling Enables Rapid and Accurate Assessment of EGFR-Activating Mutations in Tissues from Lung Cancer Patients
Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu 610065, China Targeted Tracer ...
British Swimming1mon
World Class Pathway
In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...
eLife1mon
The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling
In the mammalian central nervous system, the atypical ligand Norrin controls angiogenesis and maintenance of the blood-brain barrier and blood-retina barrier through the Wnt/β-catenin pathway. Like ...