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Severe community-acquired pneumonia (sCAP): advances in management and future directions
Severe community-acquired pneumonia (sCAP) is a major global health challenge, with high morbidity and mortality, especially ...
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Effect of viloxazine and trazodone in obstructive sleep apnoea: a randomised, placebo-controlled, cross-over study
Introduction Combination of the noradrenergic atomoxetine with either the antimuscarinic aroxybutynin or trazodone has been shown to improve obstructive sleep apnoea (OSA) severity. However, ...
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Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial
Introduction Tocilizumab improves outcomes in critically ill patients with COVID-19. Whether other immune-modulator strategies are equally effective or better is unknown. Methods We investigated ...
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Green respiratory healthcare: what really matters
The BTS/SIGN/NICE have recently published updated guidance for the treatment of asthma.1 The guideline advises that inhaler choice should be based on the lowest environmental impact among suitable ...
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Future of academic respiratory medicine: near crisis point
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
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Quality of Life Questionnaire-Bronchiectasis: final psychometric analyses and determination of minimal important difference scores
Background The Quality of Life-Bronchiectasis (QOL-B), a self-administered, patient-reported outcome measure assessing symptoms, functioning and health-related quality of life for patients with ...
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The five-repetition sit-to-stand test as a functional outcome measure in COPD
1 NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust and Imperial College, Harefield, UK 2 Harefield Pulmonary Rehabilitation Unit, Royal Brompton & Harefield ...
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Internet-based tapering of oral corticosteroids in severe asthma: a pragmatic randomised controlled trial
1 Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands 2 Department of Pulmonology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands 3 ...
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Online First
Inflammation in preschool cystic fibrosis is of mixed phenotype, extends beyond the lung and is differentially modified by CFTR modulators ...
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Chronic obstructive pulmonary disease in the older adult: what defines abnormal lung function?
1 Division of Pulmonary, Critical Care and Sleep Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA 2 Department of Medicine, Oregon Health and Science University, Portland, ...
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Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease
a Academic Department of Respiratory Medicine, St Bartholomew’s and Royal London School of Medicine and Dentistry, London Chest Hospital, London, UK, b Division of Physiological Medicine, St George’s ...