Multiple subway lines suspended service in Manhattan just ahead of the evening rush — and as the holiday travel rush was already underway — due to a water main break, according to officials.

The water main break, which happened around 1:45 p.m., also flooded the roadway in the area, snarling vehicular traffic, police said.

Rescue crews evacuated passengers from at least one stranded subway train after a water-main break halted service on the B and C lines and severely reduced service on the A and D lines.