Indiana Fever star @CaitlinClark22 and legendary Indianapolis @Colts quarterback Peyton Manning team up for a new ad for St. Vincent Hospital in Indianapolis. The Peyton Manning Children's Hospital is housed at the hospital. The ad is airing on local TV stations in the city. pic.twitter.com/BA6TeUacdv

Peyton Manning has been an Indianapolis legend for almost three decades. Caitlin Clark is now the biggest star in Naptown. Therefore, it's not surprising that a business, or in this case, a hospital,

Indiana Fever star Caitlin Clark and Indianapolis Colts legend Peyton Manning appeared in a spot for Ascension St. Vincent. The Peyton Manning Children's Hospital is located at Ascension. In the commercial, the two are in an operating room conducting a surgical procedure.

Before the commercial with Peyton Manning went live, Caitlin Clark made the rounds around the NFL world when she sat next to Taylor Swift to watch the Kansas City Chiefs beat the Houston Texans 23-14.

The Indiana Fever star and Indianapolis Colts legend appear in a new ad for Ascension St. Vincent hospital in Indianapolis.

Iowa women's basketball star and reigning WNBA Rookie of the Year for the Indiana fever, starred in a commercial with Peyton Manning

Caitlin Clark And Peyton Manning starred in a hilarious commercial for the Ascension St. Vincent hospital in downtown Indianapolis.