Frontiers12d
GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma
The role of sex hormone related signaling in macrophage proliferation was determined by immunofluorescence and flow cytometry ... Abs used are listed as follows: anti-human Cyclin E1 (4129T, CST), ...
gut.bmj6d
HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer
Perturbation experiments in GC tumour cell lines and xenograft models further demonstrated that HNF4α is downregulated by AMPKα signalling and the AMPK agonist metformin; blockade of HNF4α activity ...
Frontiers21d
YTHDC1 Regulates the Migration, Invasion, Proliferation, and Apoptosis of Rheumatoid Fibroblast-Like Synoviocytes
Background: Rheumatoid arthritis (RA), a chronic autoimmune condition, is characterized by persistent synovial inflammation, bone degradation, and progressive joint deterioration. Despite considerable ...
gut.bmj20h
Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells
2 Laboratory of Molecular Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital/Institute, ...