What is glycogen storage disease in children? Glycogen storage disease (GSD) is a rare condition that changes the way the body uses and stores glycogen, a form of sugar or glucose. Glycogen is a main ...

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack—blocking the energy supply T cells depend on. The work ...

and glycogen phosphorylase (PYG), respectively (Adeva-Andany et al, 2016). Glycogen stores are usually generated from extracellular glucose through glycogenesis. Hepatocytes and, to a lesser extent, ...

(A) In the absence of WNT binding to frizzled, dishevelled remains unactivated and β-catenin is targeted for degradation via the adenomatous polyposis coli/axin/glycogen-synthase-kinase 3β pathway.

Pompe disease is a rare, inherited metabolic disorder caused by biallelic pathogenic variants in the acid α-glucosidase (GAA) gene, which encodes a lysosomal enzyme that hydrolyzes glycogen (1 ...

Our goal was to determine mechanisms driving glycogen accumulation and its ... siRNA inhibition of glycogenolysis (liver glycogen phosphorylase, PYGL) or glycophagy (lysosomal enzyme α-acid ...

RWKV is an RNN with transformer-level LLM performance. It can be directly trained like a GPT (parallelizable). So it's combining the best of RNN and transformer - great performance, fast inference, ...

Consequently, organisms have evolved mechanisms that allow them to measure time over 24 hours and prepare for the periodic changes between light and dark. These mechanisms, known as circadian clocks, ...