PBMC were tested in antigen specific proliferation assays against peptides from myelin proteins P0, P2, PMP22, and myelin basic protein (MBP), which is identical to myelin P1, and against whole human ...

Kedia and colleagues found the Serpina3n oligodendrocytes had swelled with myelin basic protein (MBP), and their processes had fragmented, suggesting they were overwhelmed with myelin. Scanning ...

The RNA/protein combination binds to DNA near the gene for myelin basic protein, or MBP, a major component of myelin.

Here, we report that RNA-level expression of RNLTR12-int, a retrotransposon of retroviral origin, is essential for myelination. We show that RNLTR12-int-encoded RNA binds to the transcription factor ...

The research showed that levels of myelin basic protein (MBP), a key myelin protein, in these extracellular vesicles are significantly higher in MS patients than in healthy people.

By mass spectrometric quantification, the predominant Ig-CAM myelin protein zero (MPZ/P0), myelin basic protein (MBP), and the short-chain dehydrogenase 36K constitute 12%, 8%, and 6% of the total ...

Other major myelin constituents include myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG).

Multiple sclerosis has complex pathogenesis encompassing a variety of components (immunologic, genetic, and environmental). The autoimmunogenicity against the host’s myelin basic protein is a major ...

Expression of myelin basic protein (MBP)—the building block of myelin sheaths—was also lower in the hippocampi of older mice.