Denali Therapeutics Inc. DNLI announced that the FDA has granted Breakthrough Therapy Designation to its pipeline candidate, ...

DNL343 and fosigotifator are made to activate the ISR pathway protein eIF2B, but both failed to slow ALS progression in the HEALEY trial.

About a year ago, Tenvie President and Chief Scientific Officer Tony Estrada approached Denali CEO Ryan Watts and others in ...

Denali Therapeutics' DNL343 fails to slow ALS progression in phase 2/3 trial but shows safety and offers insights for future ...

Primary endpoint of overall function (ALSFRS-R) and survival, and key secondary endpoints of muscle strength and respiratory function, were not ...

The GMC Yukon Denali is a full-size SUV. Read more General Motors reviews to learn about other models. How do I know I can trust these reviews about GMC Yukon Denali? How do I know I can trust ...

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Winter Solstice is always a magical evening at Denali National Park. That’s because every year, on Dec. 21, the park’s winter crew lights a front country trail with homemade luminaries ...

President-elect Donald Trump has once again suggested he wants to revert the name of North America's tallest mountain -- Alaska's Denali -- to Mount McKinley, wading into a sensitive and decades ...

President-elect Trump pledged this week to undo former President Obama’s 2015 decision to change the name of North America’s tallest peak to its Koyukon Athabascan name "Denali," meaning "High ...

Denali was visible from Anchorage in October as a person rides a bicycle along the city's coastal trail. (Bill Roth / ADN) President-elect Donald Trump on Sunday said he wants to change the name ...