Creature Commandos will reference events in The Suicide Squad, but that doesn't mean they exist in the same continuity. James Gunn asserts the latter isn't DCU canon despite its adopted characters and stories.

James Gunn’s latest project debuts his DCU with a 94% Rotten Tomatoes score, setting the stage for connected animated and live-action projects.

In an interview with Collider, Gunn said that he doesn’t want the interconnectivity of the DCU to bog down the franchise or make viewers feel like they need to do “homework” in order to keep up with it.