Severe community-acquired pneumonia (sCAP) is a major global health challenge, with high morbidity and mortality, especially ...

Introduction Combination of the noradrenergic atomoxetine with either the antimuscarinic aroxybutynin or trazodone has been shown to improve obstructive sleep apnoea (OSA) severity. However, ...

Introduction Tocilizumab improves outcomes in critically ill patients with COVID-19. Whether other immune-modulator strategies are equally effective or better is unknown. Methods We investigated ...

The BTS/SIGN/NICE have recently published updated guidance for the treatment of asthma.1 The guideline advises that inhaler choice should be based on the lowest environmental impact among suitable ...

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Background The Quality of Life-Bronchiectasis (QOL-B), a self-administered, patient-reported outcome measure assessing symptoms, functioning and health-related quality of life for patients with ...

1 NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust and Imperial College, Harefield, UK 2 Harefield Pulmonary Rehabilitation Unit, Royal Brompton & Harefield ...

1 Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands 2 Department of Pulmonology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands 3 ...

Inflammation in preschool cystic fibrosis is of mixed phenotype, extends beyond the lung and is differentially modified by CFTR modulators ...

1 Queensland Children's Respiratory Centre, Royal Children's Hospital, Brisbane, Australia 2 Queensland Children's Medical Research Institute, University of Queensland, Brisbane, Australia 3 ...

1 Respiratory Cell and Molecular Biology, Division of Infection, Inflammation and Repair, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK 2 Department of Molecular ...